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CMPX

Compass Therapeuticsdistress 2/10 · well-funded / low risk
$2.040%today-70% from 52w high
compasstherapeutics.com39 employeesFounded 2014Boston, MABiotechnology
Oncology 2
Lead: biliary tract cancer · target PD-1
Revenue
pre-revenue
Liquidity
$195M
Runway
3.7 yrs
Shares 1y
+30%

Price & events

-67.5% over 6M
$1.67$4.18$6.69Jan 26Apr 26Jul 26159.0Mcatalyst: PHASE2,PHASE3 tovecimig (2026-04-27) — click to openrating: Citizens: Market Outperform (2026-04-28)rating: Canaccord Genuity: Buy (2026-04-28)rating: HC Wainwright & Co.: Buy (2026-04-27)rating: D. Boral Capital: Buy (2026-04-27)rating: Guggenheim: Buy (2026-03-24)
CatalystRating changeDilutionFinancingdashed = today
-0.2%
1D
-3.1%
1W
-1.2%
1M
-60.9%
3M
-65.5%
6M
-38.9%
1Y
+97.6%
2Y
-58.9%
5Y
-76.1%
All

Overview

Market Cap
$366.48M
Volume
106.44K
52 Week Range
$1.67 – $6.69
Total Shares
180.09M
Float Shares
122.69M
Short %
24.65%
% Held by Insiders
12.46%
% Held by Institutions
93.79%
RVOL
0.04x
Beta
0.75

Pipeline stages · 2 programs

CTX-10726
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-12
CTX-471, Pembrolizumab (KEYTRUDA®)PD-1
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved

Pipeline · 5 trials · 3 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2026-12-01
Estimated 50%
readout ~2027-02-14
Phase 2/3CTX-009, PaclitaxelBiliary Tract Cancer, Cholangiocarcinoma, Gall Bladder Cancer, Ampullary Canceractive not recruiting
2026-12
Estimated 50%
readout ~2026-12-31
Phase 1CTX-8371Non Small Cell Lung Cancer, Triple Negative Breast Cancer, Hodgkin Lymphoma, Head and Neck Squamous Cell Carcinoma, Malignant Melanomarecruiting
2028-04-01
Estimated 50%
readout ~2028-05-01
Phase 1CTX-10726Gastroesophageal Cancer (GC), Hepatocellular Carcinoma (HCC), Endometrial Cancer, Renal Cell Carcinoma (RCC)recruiting
2025-05-21
Phase 1CTX-471, Pembrolizumab (KEYTRUDA®)Locally Advanced Solid Tumor, Metastatic Cancer, Non-small Cell Lung Cancer, Small Cell Lung Cancer, Mesothelioma, Melanoma, Head and Neck Cancer100completed
2025-05-15
Phase 2CTX-009Metastatic Colorectal Cancer, Colon Cancer, Rectal Cancer49completed

Catalyst news & presentations · 3

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 180,087,915 · 2 offerings/1y · 0 PIPEs
  • 2026-01-07EFFECTshelf_effective
  • 2025-12-30S-3shelf_registration
  • 2025-08-138-Kmaterial_agreement
  • 2025-08-13424B5offering
  • 2025-08-12424B5offering
  • 2024-11-14SC 13G/Astrategic_stake
  • 2024-09-06EFFECTshelf_effective
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

strong buy · target $9 (+318% upside) · 12 analysts
  • 2026-04-28CitizensMarket Outperform
  • 2026-04-28Canaccord GenuityBuy
  • 2026-04-27HC Wainwright & Co.Buy
  • 2026-04-27D. Boral CapitalBuy
  • 2026-03-24GuggenheimBuy
  • 2026-01-06D. Boral CapitalBuy

Competitors — PD-1

  • REGNREGENERON PHARMACEUTICALS, INC.$60.4B · D2
  • BEIGFBeOne Medicines Ltd.$31.7B · D1
  • NCNANuCana plc$28.3B · D2
  • EXELEXELIXIS, INC.$13.8B · D0
  • IOVAIOVANCE BIOTHERAPEUTICS, INC.$2.3B · D4
  • CGEMCullinan Therapeutics, Inc.$1.1B · D1
  • REPLReplimune Group, Inc.$906M · D2
  • ALXOALX ONCOLOGY HOLDINGS INC$262M · D5
  • BCABBioAtla, Inc.$107M · D8
  • IOBTQIO Biotech, Inc.$71,949 · D5

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.