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NCNA

NuCana plcdistress 2/10 · well-funded / low risk
$1.360%today-89% from 52w high
nucana.com10 employeesFounded 1997Edinburgh, United KingdomBiotechnology
Oncology 2
Lead: Advanced Cancer · target PD-1
Revenue
pre-revenue
Liquidity
$22M
Runway
2.9 yrs
Shares 1y
0%

Price & events

-57.8% over 6M
$1.24$2.25$3.26Jan 26Apr 26Jul 26210k
CatalystRating changeDilutionFinancingdashed = today
+0.0%
1D
+2.3%
1W
-21.4%
1M
-36.7%
3M
-58.3%
6M
-87.2%
1Y
-99.8%
2Y
-100.0%
5Y
-100.0%
All

Overview

Market Cap
$28.30B
Volume
5.90K
52 Week Range
$1.24 – $12.00
Total Shares
20.81B
Float Shares
4.16M
Short %
2.78%
% Held by Insiders
0.00%
% Held by Institutions
1.38%
RVOL
0.10x
Beta
2.24

Pipeline stages · 2 programs

NUC-7738, PembrolizumabPD-1
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-08
Fosifloxuridine Nafalbenamide, Leucovorin, PembrolizumabPD-1
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved

Pipeline · 2 trials · 1 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2026-08
Estimated 50%
readout ~2026-09-15
Phase 1/2NUC-7738, PembrolizumabAdvanced Cancer, Lymphoma, Solid Tumor, Melanoma135recruiting
2025-05-30
Phase 1/2Fosifloxuridine Nafalbenamide, Leucovorin, PembrolizumabAdvanced Cancer, Advanced Solid Tumor, Neoplasm Malignant, Metastatic Cancer, Melanoma, Classical Hodgkin Lymphoma, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Urothelial Carcinoma, Head and Neck Squamous Cell Carcinoma, Subungual Squamous Cell Carcinoma, Oesophageal Carcinoma, MSI-H Colorectal Cancer, Gastric Cancer, Triple Negative Breast Cancer, Endometrial Carcinoma, Pleural Mesothelioma19terminated

Catalyst news & presentations · 0

  • No catalyst news yet.

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 20,809,854,947 · 0 offerings/1y · 0 PIPEs
  • 2025-06-27424B5offering
  • 2025-06-24EFFECTshelf_effective
  • 2025-06-18F-3/Ashelf_registration
  • 2025-05-07424B4offering
  • 2025-05-05EFFECTshelf_effective
  • 2025-05-05EFFECTshelf_effective
  • 2025-05-02F-1/Ashelf_registration
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
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🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

no consensus
  • 2024-08-19OppenheimerOutperform
  • 2024-07-23OppenheimerOutperform
  • 2024-07-22OppenheimerOutperform

Competitors — PD-1

  • REGNREGENERON PHARMACEUTICALS, INC.$60.4B · D2
  • BEIGFBeOne Medicines Ltd.$31.7B · D1
  • EXELEXELIXIS, INC.$13.8B · D0
  • TNGXTango Therapeutics, Inc.$4.0B · D5
  • IOVAIOVANCE BIOTHERAPEUTICS, INC.$2.3B · D4
  • CGEMCullinan Therapeutics, Inc.$1.1B · D1
  • REPLReplimune Group, Inc.$906M · D2
  • ALXOALX ONCOLOGY HOLDINGS INC$262M · D5
  • BCABBioAtla, Inc.$107M · D8
  • IOBTQIO Biotech, Inc.$71,949 · D5

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.