CatalystMarker
← board

ALXO

ALX Oncology Inc.distress 5/10 · elevated risk
$1.95-3%today-25% from 52w high
alxoncology.com43 employeesFounded 2015South San Francisco, CABiotechnology
Oncology 3
Lead: Head and Neck Cancer · target PD-1
Revenue
pre-revenue
Liquidity
$169M
Runway
2.2 yrs
Shares 1y
+151%

Price & events

+32.7% over 6M
$1.37$1.98$2.60Jan 26Apr 26Jul 2614.5Mdilution: 424B5 offering (2026-01-30)financing: 8-K material_agreement (2026-06-26)financing: 8-K material_agreement (2026-01-30)rating: Wells Fargo: Overweight (2026-03-19)rating: HC Wainwright & Co.: Buy (2026-03-10)rating: Piper Sandler: Overweight (2026-02-05)
CatalystRating changeDilutionFinancingdashed = today
-3.5%
1D
-5.8%
1W
+10.8%
1M
+22.6%
3M
+39.3%
6M
+285.4%
1Y
-70.7%
2Y
-96.7%
5Y
-97.6%
All

Overview

Market Cap
$262.40M
Enterprise Value
$233.41M
Volume
46.85K
52 Week Range
$0.47 – $2.60
Total Shares
134.56M
Float Shares
77.44M
Short %
5.22%
% Held by Insiders
0.92%
% Held by Institutions
78.79%
RVOL
0.03x
Beta
0.43

Pipeline stages · 2 programs

ALX2004
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-06
Evorpacept (ALX148), Trastuzumab, Paclitaxel
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-12

Pipeline · 6 trials · 2 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2027-06
Estimated 50%
readout ~2027-07-01
Phase 1ALX2004NSCLC (Advanced Non-small Cell Lung Cancer), HNSCC, CRC (Colorectal Cancer), ESCC, Colo-rectal Cancer, Head and Neck Cancer, Esophageal Squamous Cell Carcinoma (ESCC)recruiting
2027-12
Estimated 50%
readout ~2028-01-15
Phase 2Evorpacept (ALX148), Trastuzumab, PaclitaxelBreast Cancer, Metastaticrecruiting
2025-06-27
Phase 1Evorpacept, Enfortumab VedotinBladder Cancer, Urothelial Carcinoma36completed
2025-03-03
Phase 2evorpacept, pembrolizumabHead and Neck Cancer, Head and Neck Squamous Cell Carcinoma189active not recruiting
2025-03-03
Phase 2evorpacept, pembrolizumab, Cisplatin/Carboplatin; 5FUHead and Neck Cancer, Head and Neck Squamous Cell Carcinoma172active not recruiting
Show all 6 trials · 1 more ▾
ReadoutPhaseDrugIndicationEnrollStatus
2025-01-17
Phase 1evorpacept, azacitidineHigher Risk Myelodysplastic Syndromes65terminated

Upcoming readouts & decisions · our signals

1 upcoming event has our read — the sell-the-news timing call plus an experimental clinical estimate. Go Pro to see them.

Catalyst news & presentations · 4

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 134,562,917 · 1 offerings/1y · 0 PIPEs
  • 2026-06-268-Kmaterial_agreement
  • 2026-01-308-Kmaterial_agreement
  • 2026-01-30424B5offering
  • 2025-04-24EFFECTshelf_effective
  • 2025-03-06S-3shelf_registration
  • 2024-11-14SC 13G/Astrategic_stake
  • 2024-11-14SC 13G/Astrategic_stake
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
Upgrade to Pro

Wall St ratings

no consensus
  • 2026-03-19Wells FargoOverweight
  • 2026-03-10HC Wainwright & Co.Buy
  • 2026-02-05Piper SandlerOverweight
  • 2025-05-21UBSBuy
  • 2025-05-09HC Wainwright & Co.Buy
  • 2025-03-07StifelHold

Competitors — PD-1

  • REGNREGENERON PHARMACEUTICALS, INC.$60.4B · D2
  • BEIGFBeOne Medicines Ltd.$31.7B · D1
  • NCNANuCana plc$28.3B · D2
  • EXELEXELIXIS, INC.$13.8B · D0
  • TNGXTango Therapeutics, Inc.$4.0B · D5
  • IOVAIOVANCE BIOTHERAPEUTICS, INC.$2.3B · D4
  • CGEMCullinan Therapeutics, Inc.$1.1B · D1
  • REPLReplimune Group, Inc.$906M · D2
  • BCABBioAtla, Inc.$107M · D8
  • IOBTQIO Biotech, Inc.$71,949 · D5

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.