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LYRA

Lyra Therapeuticsdistress 6/10 · elevated risk
$0.520%today-94% from 52w high
lyratherapeutics.com27 employeesFounded 2005Watertown, MABiotechnology
Lead: chronic rhinosinusitis
Revenue
pre-revenue
Liquidity
$16M
Runway
0.6 yrs
Shares 1y
+8%

Price & events

-76.4% over 6M
$0.37$1.29$2.20Jan 26Apr 26Jul 261.4Mdilution: EFFECT shelf_effective (2026-03-26)dilution: EFFECT shelf_effective (2026-03-26)dilution: EFFECT shelf_effective (2026-03-26)catalyst: PHASE3 LYR-210 (2026-06-30) — click to open
CatalystRating changeDilutionFinancingdashed = today
+0.0%
1D
-0.5%
1W
-8.8%
1M
-31.7%
3M
-76.4%
6M
-93.7%
1Y
-96.4%
2Y
-99.9%
5Y
-99.9%
All

Overview

Market Cap
$922.94K
Volume
0
52 Week Range
$0.37 – $8.71
Total Shares
1.77M
Float Shares
336.13K
Short %
1.10%
% Held by Insiders
0.62%
% Held by Institutions
12.53%
Beta
0.69

Pipeline stages · 1 programs

LYR-210, Sham procedure control
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved

Pipeline · 1 trials · 0 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2025-04-02
Phase 3LYR-210, Sham procedure controlChronic Sinusitis, Chronic Rhinosinusitis (Diagnosis)182completed

Catalyst news & presentations · 5

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 1,774,882 · 1 offerings/1y · 0 PIPEs
  • 2026-03-26EFFECTshelf_effective
  • 2026-03-26EFFECTshelf_effective
  • 2026-03-26EFFECTshelf_effective
  • 2025-07-31424B3offering
  • 2025-07-30EFFECTshelf_effective
  • 2025-07-22S-1shelf_registration
  • 2025-06-278-Kprivate_placement
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
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🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

no consensus
  • 2025-08-14HC Wainwright & Co.Neutral
  • 2025-06-10HC Wainwright & Co.Neutral
  • 2025-03-14HC Wainwright & Co.Neutral
  • 2024-08-15Cantor FitzgeraldOverweight
  • 2024-08-15HC Wainwright & Co.Neutral

Competitors — chronic rhinosinusitis

  • LLYELI LILLY & Co$1094.4B · D3
  • SNYSanofi$52.5B · D1
  • UPBUpstream Bio, Inc.$353M · D3
  • AZNASTRAZENECA PLC · D3

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.