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SLN

Silence Therapeutics plcdistress 4/10 · elevated risk
$11.63-2%today-2% from 52w high
silence-therapeutics.com88 employeesFounded 1994London, United KingdomBiotechnology
Lead: Polycythemia Vera
Revenue
pre-revenue
Liquidity
$70M
Runway
1.1 yrs
Shares 1y
0%

Price & events

+99.8% over 6M
$4.30$8.07$11.83Jan 26Apr 26Jul 262.2Mrating: Cantor Fitzgerald: Overweight (2026-06-24)rating: HC Wainwright & Co.: Buy (2026-06-17)rating: HC Wainwright & Co.: Buy (2026-03-13)
CatalystRating changeDilutionFinancingdashed = today
-1.7%
1D
+6.5%
1W
+60.0%
1M
+48.3%
3M
+105.1%
6M
+89.1%
1Y
-46.5%
2Y
-53.5%
5Y
-51.5%
All

Overview

Market Cap
$1.65B
Volume
43.01K
52 Week Range
$4.30 – $11.83
Total Shares
141.70M
Float Shares
27.46M
Short %
4.86%
% Held by Insiders
21.77%
% Held by Institutions
44.57%
RVOL
0.08x
Beta
1.38

Pipeline stages · 1 programs

SLN124
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-09

Pipeline · 1 trials · 1 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2026-09
Estimated 50%
readout ~2026-10-16
Phase 1/2SLN124Polycythemia Veraactive not recruiting

Catalyst news & presentations · 1

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 141,703,840 · 0 offerings/1y · 0 PIPEs
  • none
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
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🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

buy · target $29 (+151% upside) · 6 analysts
  • 2026-06-24Cantor FitzgeraldOverweight
  • 2026-06-17HC Wainwright & Co.Buy
  • 2026-03-13HC Wainwright & Co.Buy
  • 2025-09-16HC Wainwright & Co.Buy
  • 2025-08-08Chardan CapitalBuy
  • 2025-06-13Chardan CapitalBuy

Competitors — Polycythemia Vera

  • MRKMerck & Co., Inc.$318.8B · D3
  • GSKGSK plc$217.0B · D1
  • TKPHFTAKEDA PHARMACEUTICAL CO LTD$53.7B · D1
  • INCYINCYTE CORP$23.1B · D0
  • IONSIONIS PHARMACEUTICALS INC$9.2B · D2
  • PTGXProtagonist Therapeutics, Inc$8.6B · D0
  • IRONDisc Medicine, Inc.$2.8B · D1
  • AGIOAGIOS PHARMACEUTICALS, INC.$2.1B · D5
  • PRLDPrelude Therapeutics Inc$307M · D6
  • SLNCFSilence Therapeutics plc$213M · D5

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.