CatalystMarker
← board

MGNX

MacroGenicsdistress 4/10 · elevated risk
$4.14-4%today-15% from 52w high
macrogenics.com293 employeesFounded 2000Rockville, MDBiotechnology
Oncology 2
Lead: Leukemia · est. market ~$15B (approx, global)
Revenue
$21M
Liquidity
$67M
Runway
0.9 yrs
Shares 1y
+1%

Price & events

+135.0% over 6M
$1.70$3.28$4.86Jan 26Apr 26Jul 2614.0Mfinancing: 8-K material_agreement (2026-05-12)financing: 8-K material_agreement (2026-05-04)catalyst: PHASE2 lorigerlimab, docetaxel, Prednisone (2026-02-19) — click to openrating: Barclays: Overweight (2026-04-20)rating: B. Riley Securities: Neutral → Buy (2026-04-10)rating: Barclays: Overweight (2026-03-10)
CatalystRating changeDilutionFinancingdashed = today
-3.8%
1D
+0.4%
1W
-11.8%
1M
+30.1%
3M
+129.8%
6M
+128.5%
1Y
-22.4%
2Y
-84.0%
5Y
-81.4%
All

Overview

Market Cap
$262.91M
Volume
33.87K
52 Week Range
$1.33 – $4.86
Total Shares
63.56M
Float Shares
55.88M
Short %
10.81%
% Held by Insiders
3.43%
% Held by Institutions
71.08%
RVOL
0.03x
Beta
1.18

Pipeline stages · 5 programs

MGC028
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-11
MGD024
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-11
Lorigerlimab
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-07
MGC026 Dose Escalation, MGC026 Dose for Expansion
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2028-05
vobramitamab duocarmazine, lorigerlimab
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved

Pipeline · 6 trials · 4 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2026-11
Estimated 50%
readout ~2026-12-01
Phase 1MGC028Advanced Solid Tumors, NSCLC Adenocarcinoma, Cholangiocarcinoma, Pancreatic Carcinoma, Colorectal Carcinomarecruiting
2026-11
Estimated 50%
readout ~2026-12-01
Phase 1MGD024Leukemia, Acute Myeloid, Myelodysplastic Syndromes, Classical Hodgkin Lymphoma, Leukemia, B-cell, Leukemia, Hairy Cell, Mastocytosis, Aggressive Systemic, Blastic Plasmacytoid Dendritic Cell Neoplasm, Chronic Myeloid Leukemiarecruiting
2027-07
Estimated 50%
readout ~2027-08-15
Phase 2LorigerlimabPlatinum-resistant Ovarian Cancer, Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Clear Cell Adenocarcinoma of Ovary, Clear Cell Adenocarcinoma of Vulva, Clear Cell Adenocarcinoma of Vagina, Clear Cell Adenocarcinoma of Cervix, Clear Cell Adenocarcinoma of Uterus, Clear Cell Adenocarcinoma of Fallopian Tube, Clear Cell Adenocarcinoma of Peritoneum, Endometrial Cancerrecruiting
2028-05
Estimated 50%
readout ~2028-05-31
Phase 1MGC026 Dose Escalation, MGC026 Dose for ExpansionAdvanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Squamous Cell Carcinoma of Head and Neck, Non Small Cell Lung Cancer, Small-cell Lung Cancer, Bladder Cancer, Sarcoma, Endometrial Cancer, Melanoma, Castration Resistant Prostatic Cancer, Cervical Cancer, Colorectal Cancer, Gastric Cancer, Gastro-esophageal Cancer, Pancreas Cancer, Clear Cell Renal Cell Carcinoma, Hepatocellular Carcinoma, Platinum-resistant Ovarian Cancer, Breast Cancer, Ovarian Cancer, Esophageal Squamous Cell Cancer (SCC)recruiting
2026-02-19
Phase 2lorigerlimab, docetaxel, PrednisoneAndrogen-Independent Prostatic Cancer, Androgen-Independent Prostatic Neoplasms, Prostate Cancer Recurrent, Androgen-Insensitive Prostatic Cance, Androgen-Resistant Prostatic Cancer, Hormone Refractory Prostatic Cancer, Immunotherapy, Immune Checkpoint Inhibitor, Inhibitory Checkpoint Molecule154completed
Show all 6 trials · 1 more ▾
ReadoutPhaseDrugIndicationEnrollStatus
2025-06-24
Phase 1vobramitamab duocarmazine, lorigerlimabAdvanced Solid Tumor, Castration-Resistant Prostatic Cancer, Malignant Melanoma, Pancreatic Ductal Carcinoma, Hepatocellular Cancer, Epithelial Ovarian Cancer, Renal Cell Carcinoma31completed

Catalyst news & presentations · 6

Approved drugs (1)

  • MARGENZAMARGETUXIMAB-CMKB2020 · Prescription

Capital structure — dilution & financing

Shares out: 63,563,123 · 0 offerings/1y · 0 PIPEs
  • 2026-05-128-Kmaterial_agreement
  • 2026-05-048-Kmaterial_agreement
  • 2025-06-108-Kmaterial_agreement
  • 2024-11-20SC 13Gstrategic_stake
  • 2024-11-14SC 13G/Astrategic_stake
  • 2024-11-08SC 13G/Astrategic_stake
  • 2024-10-22SC 13G/Astrategic_stake
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
Upgrade to Pro

Wall St ratings

no consensus
  • 2026-04-20BarclaysOverweight
  • 2026-04-10B. Riley SecuritiesNeutral → Buy
  • 2026-03-10BarclaysOverweight
  • 2025-11-03HC Wainwright & Co.Neutral
  • 2025-08-15Leerink PartnersOutperform
  • 2025-05-20B. Riley SecuritiesNeutral

Competitors — Leukemia

  • JNJJOHNSON & JOHNSON$617.4B · D0
  • ABBVAbbVie Inc.$451.1B · D2
  • MRKMerck & Co., Inc.$318.8B · D3
  • NVSEFNOVARTIS AG$292.0B · D3
  • BEIGFBeOne Medicines Ltd.$31.7B · D1
  • NRIXNurix Therapeutics, Inc.$2.4B · D6
  • SNDXSyndax Pharmaceuticals Inc$1.9B · D5
  • KURAKura Oncology, Inc.$917M · D5
  • INABIN8BIO, INC.$12M · D7
  • AZNASTRAZENECA PLC · D3

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.