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CCCC

C4 Therapeutics, Inc.distress 5/10 · elevated risk
$3.69-1%today-21% from 52w high
c4therapeutics.com104 employeesFounded 2015Watertown, MABiotechnology
Oncology 1
Lead: multiple myeloma · est. market ~$25B (approx, global)
Revenue
pre-revenue
Liquidity
$378M
Runway
4.0 yrs
Shares 1y
+55%

Price & events

+69.1% over 6M
$1.71$3.19$4.67Jan 26Apr 26Jul 2620.1Mfinancing: 8-K material_agreement (2026-04-09)catalyst: PHASE1 cemsidomide (2026-06-30) — click to opencatalyst: cemsidomide (2026-03-31) — click to openrating: Evercore ISI Group: Outperform (2026-06-01)rating: Barclays: Overweight (2026-02-27)rating: Brookline Capital: Buy (2026-02-23)
CatalystRating changeDilutionFinancingdashed = today
-1.4%
1D
+3.0%
1W
-12.6%
1M
+24.1%
3M
+71.5%
6M
+52.3%
1Y
-43.1%
2Y
-91.0%
5Y
-88.5%
All

Overview

Market Cap
$407.64M
Volume
125.44K
52 Week Range
$1.71 – $4.67
Total Shares
110.57M
Float Shares
83.71M
Short %
22.76%
% Held by Insiders
0.93%
% Held by Institutions
85.31%
RVOL
0.03x
Beta
2.91

Pipeline stages · 2 programs

Cemsidomide, Dexamethasone
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-09-30
CFT1946, Trametinib, Cetuximab
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved

Pipeline · 4 trials · 3 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2026-09-30
Estimated 50%
readout ~2026-10-30
Phase 1cemsidomide, Dexamethasone OralMultiple Myeloma, Lymphoma, Non-Hodgkin'sactive not recruiting
2028-12
Estimated 50%
readout ~2028-12-31
Phase 1Cemsidomide, ElranatamabMultiple Myeloma (MM)recruiting
2030-03
Estimated 50%
readout ~2030-04-15
Phase 2Cemsidomide, DexamethasoneMultiple Myeloma, Relapsed/Refractory Multiple Myelomarecruiting
2025-11-05
Phase 1CFT1946, Trametinib, CetuximabSolid Tumors, Melanoma, NSCLC, CRC, ATC89completed

Catalyst news & presentations · 10

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 110,567,222 · 3 offerings/1y · 0 PIPEs
  • 2026-04-098-Kmaterial_agreement
  • 2025-12-10424B5offering
  • 2025-12-10EFFECTshelf_effective
  • 2025-11-21S-3shelf_registration
  • 2025-10-168-Kmaterial_agreement
  • 2025-10-16FWPoffering
  • 2025-10-16424B5offering
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

strong buy · target $13 (+262% upside) · 6 analysts
  • 2026-06-01Evercore ISI GroupOutperform
  • 2026-02-27BarclaysOverweight
  • 2026-02-23Brookline CapitalBuy
  • 2025-12-17BarclaysOverweight
  • 2025-12-02TD CowenBuy
  • 2025-09-23Wells FargoOverweight

Competitors — multiple myeloma

  • JNJJOHNSON & JOHNSON$617.4B · D0
  • ABBVAbbVie Inc.$451.1B · D2
  • GSKGSK plc$217.0B · D1
  • PFEPFIZER INC$142.2B · D3
  • BMYBRISTOL MYERS SQUIBB CO$124.5B · D0
  • REGNREGENERON PHARMACEUTICALS, INC.$60.4B · D2
  • DTILPRECISION BIOSCIENCES INC$185M · D6
  • CRBUCaribou Biosciences, Inc.$160M · D0
  • TPSTTempest Therapeutics, Inc.$14M · D10
  • AZNASTRAZENECA PLC · D3

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.