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ORKA

Oruka Therapeutics, Inc.distress 5/10 · elevated risk
$91.45-1%today-4% from 52w high
orukatx.com68 employeesMenlo Park, CABiotechnology
Immunology / Inflammation 1
Lead: Plaque Psoriasis · target IL-23 · est. market ~$30B (approx, global)
Revenue
pre-revenue
Liquidity
$496M
Runway
5.5 yrs
Shares 1y
+61%

Price & events

+157.4% over 6M
$31.42$63.29$95.17Jan 26Apr 26Jul 267.9Mdilution: 424B5 offering (2026-04-29)dilution: 424B5 offering (2026-04-27)dilution: 424B5 offering (2026-04-27)dilution: 424B7 offering (2026-04-21)dilution: EFFECT shelf_effective (2026-04-10)dilution: S-3 shelf_registration (2026-04-02)catalyst: PHASE2 ORKA-001 Induction Dose, ORKA-001 Maintenance Dose (2026-04-01) — click to opencatalyst: PHASE1 ORKA-001 (2026-03-13) — click to openrating: BTIG: Buy (2026-07-13)rating: UBS: Buy (2026-07-01)rating: HC Wainwright & Co.: Buy (2026-06-23)rating: HC Wainwright & Co.: Buy (2026-05-18)rating: BTIG: Buy (2026-05-14)rating: HC Wainwright & Co.: Buy (2026-04-29)rating: UBS: Buy (2026-04-28)rating: Barclays: Overweight (2026-04-28)
CatalystRating changeDilutionFinancingdashed = today
-1.2%
1D
+10.1%
1W
+9.7%
1M
+35.0%
3M
+165.9%
6M
+529.0%
1Y
+354.2%
2Y
+377.1%
5Y
+240.6%
All

Overview

Market Cap
$5.52B
Volume
60.66K
52 Week Range
$13.05 – $95.17
Total Shares
60.31M
Float Shares
51.09M
Short %
23.15%
% Held by Insiders
1.23%
% Held by Institutions
89.77%
RVOL
0.04x

Pipeline stages · 1 programs

ORKA-001
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-06

Pipeline · 5 trials · 3 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2027-06
Estimated 50%
readout ~2027-07-16
Phase 2ORKA-001Plaque Psoriasisrecruiting
2027-10
Estimated 50%
readout ~2027-11-15
Phase 2ORKA-002Plaque Psoriasisrecruiting
2030-05
Estimated 50%
readout ~2030-06-15
Phase 2ORKA-001Plaque Psoriasisrecruiting
2026-04
Phase 2ORKA-001 Induction Dose, ORKA-001 Maintenance DosePlaque Psoriasis80active not recruiting
2026-03-13
Phase 1ORKA-001Healthy Volunteers24completed

Catalyst news & presentations · 4

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 60,312,101 · 8 offerings/1y · 1 PIPEs
  • 2026-04-29424B5offering
  • 2026-04-27424B5offering
  • 2026-04-27424B5offering
  • 2026-04-21424B7offering
  • 2026-04-10EFFECTshelf_effective
  • 2026-04-02S-3shelf_registration
  • 2025-11-05424B5offering
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

strong buy · target $145 (+58% upside) · 12 analysts
  • 2026-07-13BTIGBuy
  • 2026-07-01UBSBuy
  • 2026-06-23HC Wainwright & Co.Buy
  • 2026-05-18HC Wainwright & Co.Buy
  • 2026-05-14BTIGBuy
  • 2026-04-29HC Wainwright & Co.Buy

Competitors — IL-23

  • none identified

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.