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OPK

OPKO Health, Inc.distress 0/10 · well-funded / low risk
$1.180%today-25% from 52w high
opko.com2,275 employeesFounded 2006Miami, FLDiagnostics & Research
Lead: Advanced Tumors
Revenue
$124M
Liquidity
$342M
Runway
2.1 yrs
Shares 1y
-2%

Price & events

-13.2% over 6M
$1.10$1.31$1.53Jan 26Apr 26Jul 2610.1Mrating: Barrington Research: Outperform → Market Perform (2026-04-29)rating: Barrington Research: Outperform (2026-03-02)
CatalystRating changeDilutionFinancingdashed = today
+0.0%
1D
-0.8%
1W
-19.2%
1M
-3.3%
3M
-10.6%
6M
-17.5%
1Y
-18.1%
2Y
-67.6%
5Y
-71.9%
All

Overview

Market Cap
$891.01M
Enterprise Value
$561.15M
Volume
257.03K
52 Week Range
$1.10 – $1.58
Total Shares
755.09M
Float Shares
332.82M
Short %
7.70%
% Held by Insiders
49.95%
% Held by Institutions
27.02%
RVOL
0.09x
Beta
1.48

Pipeline stages · 5 programs

CTAP101
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-10
OPK-88006
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-12
MDX2003
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2028-01
MDX2001
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2028-08
MDX2004
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2031-06-30

Pipeline · 5 trials · 5 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2027-10
Estimated 50%
readout ~2027-11-15
Phase 2CTAP101CKD Stage 3, CKD Stage 4, Secondary Hyperparathyroidism, VDInot yet recruiting
2027-12
Estimated 50%
readout ~2028-01-15
Phase 1/2OPK-88006MASHnot yet recruiting
2028-01
Estimated 50%
readout ~2028-02-15
Phase 1/2MDX2003Lymphoma, Waldenström Macroglobulinemia (WM), DLBCL - Diffuse Large B Cell Lymphoma, PMBCL, HGBCL, FL Lymphoma, Lymphoplasmacytic Lymphoma, Follicular Lymphoma (FL)recruiting
2028-08
Estimated 50%
readout ~2028-09-15
Phase 1/2MDX2001Biliary Tract Cancer, Breast Cancer, Cervical Cancer, Colon Cancer, Endometrial Cancer, Esophageal Cancer, Gastric Cancer, GastroEsophageal Cancer, Head and Neck Cancer, Hepatocellular Cancer, Non-small Cell Lung Cancer, Pancreatic Cancer, Prostate Cancer, Rectal Cancer, Renal Cancer, Thyroid Cancerrecruiting
2031-06-30
Estimated 50%
readout ~2031-08-14
Phase 1/2MDX2004Advanced Tumorsrecruiting

Catalyst news & presentations · 3

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 755,092,256 · 0 offerings/1y · 0 PIPEs
  • 2025-04-018-Kprivate_placement
  • 2025-03-288-Kprivate_placement
  • 2025-03-118-Kmaterial_agreement
  • 2024-11-20SC 13D/Astrategic_stake
  • 2024-11-15SC 13D/Astrategic_stake
  • 2024-11-13SC 13Gstrategic_stake
  • 2024-11-12SC 13G/Astrategic_stake
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
Upgrade to Pro

Wall St ratings

buy · target $4 (+271% upside) · 4 analysts
  • 2026-04-29Barrington ResearchOutperform → Market Perform
  • 2026-03-02Barrington ResearchOutperform
  • 2025-11-20JP MorganNeutral
  • 2025-10-31JefferiesBuy → Hold
  • 2025-10-30Barrington ResearchOutperform
  • 2025-05-01Barrington ResearchOutperform

Competitors — Advanced Tumors

  • none identified

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.