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ARWR

Arrowhead Pharmaceuticalsdistress 3/10 · well-funded / low risk
$87.25-2%today-2% from 52w high
arrowheadpharma.com711 employeesFounded 2003Pasadena, CABiotechnology
Metabolic / Obesity 2Nephrology 1Neurology 1Respiratory 1
Lead: Severe Hypertriglyceridemia · target APOC3
Revenue
$338M
Liquidity
$1784M
Runway
Shares 1y
+2%

Price & events

+25.4% over 6M
$55.01$71.85$88.70Jan 26Apr 26Jul 2624.1Mcatalyst: PHASE3 Plozasiran Injection (2026-06-01) — click to opencatalyst: PHASE3 Plozasiran Injection (2026-06-01) — click to opencatalyst: PHASE1,PHASE2 ARO-DIMERPA (2026-06-01) — click to openrating: JP Morgan: Overweight (2026-07-17)rating: Stifel: Buy (2026-07-14)rating: HC Wainwright & Co.: Buy (2026-07-01)rating: Chardan Capital: Buy (2026-06-30)rating: Leerink Partners: Market Perform (2026-06-17)rating: Bernstein: Market Perform (2026-05-13)rating: RBC Capital: Outperform (2026-05-08)rating: JP Morgan: Overweight (2026-05-01)
CatalystRating changeDilutionFinancingdashed = today
-1.6%
1D
+22.2%
1W
+9.2%
1M
+17.3%
3M
+30.1%
6M
+448.0%
1Y
+203.1%
2Y
+27.6%
5Y
+16.6%
All

Overview

Market Cap
$12.29B
Volume
190.22K
52 Week Range
$14.71 – $88.70
Total Shares
140.86M
Float Shares
122.78M
Short %
8.34%
% Held by Insiders
3.68%
% Held by Institutions
88.91%
RVOL
0.07x
Beta
1.26

Pipeline stages · 3 programs

ARO-RAGE
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-10
Zodasiran
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-08-20
Plozasiran
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2028-07

Pipeline · 17 trials · 10 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2026-10
Estimated 50%
readout ~2026-11-15
Phase 1/2ARO-ALK7Obesity, Diabetes Mellitus, Type 2recruiting
2026-12
Estimated 50%
readout ~2027-01-15
Phase 1/2ARO-DUX4 for InjectionFacio-Scapulo-Humeral Dystrophyrecruiting
2026-12
Estimated 50%
readout ~2027-01-15
Phase 1/2ARO-DM1 Intravenous (IV) Infusion, ARO-DM1 subcutaneous (SC) injectionMyotonic Dystrophy 1recruiting
2027-06
Estimated 50%
readout ~2027-07-16
Phase 1/2ARO-MAPT-SCAlzheimer Disease, Alzheimer Disease, Early Onsetrecruiting
2027-08-20
Estimated 50%
readout ~2027-11-03
Phase 3zodasiran InjectionHomozygous Familial Hypercholesterolemiarecruiting
Show all 17 trials · 12 more ▾
ReadoutPhaseDrugIndicationEnrollStatus
2027-09-17
Estimated 50%
readout ~2027-11-01
Phase 1/2ARO-INHBE, TirzepatideObesityrecruiting
2027-12
Estimated 50%
readout ~2028-01-15
Phase 2ARO-RAGEAsthmarecruiting
2028-07
Estimated 50%
readout ~2028-09-14
Phase 3Plozasiran InjectionHypertriglyceridemiarecruiting
2028-07
Estimated 50%
readout ~2028-09-14
Phase 3ZodasiranHomozygous Familial Hypercholesterolemianot yet recruiting
2029-03
Estimated 50%
readout ~2029-05-15
Phase 3PlozasiranSevere Hypertriglyceridemiarecruiting
2026-06
Phase 3Plozasiran InjectionSevere Hypertriglyceridemia311active not recruiting
2026-06
Phase 3Plozasiran InjectionSevere Hypertriglyceridemia446active not recruiting
2026-06
Phase 1/2ARO-DIMERPAHyperlipidemia; Mixed78recruiting
2025-09-22
Phase 2ARO-APOC3Dyslipidemias418completed
2025-04-16
Phase 1/2ARO-RAGEAsthma127completed
2025-03-31
Phase 1ARO-CFBIgA Nephropathy49completed
2025-03
Phase 1ARO-SOD1 InjectionAmyotrophic Lateral Sclerosis0withdrawn

Catalyst news & presentations · 1

Approved drugs (1)

  • REDEMPLOPLOZASIRAN SODIUM2025 · Prescription

Capital structure — dilution & financing

Shares out: 140,857,021 · 6 offerings/1y · 0 PIPEs
  • 2026-01-128-Kmaterial_agreement
  • 2026-01-098-Kmaterial_agreement
  • 2026-01-09424B5offering
  • 2026-01-09424B5offering
  • 2026-01-08FWPoffering
  • 2026-01-08FWPoffering
  • 2026-01-07424B5offering
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
Upgrade to Pro

Wall St ratings

strong buy · target $96 (+10% upside) · 11 analysts
  • 2026-07-17JP MorganOverweight
  • 2026-07-14StifelBuy
  • 2026-07-01HC Wainwright & Co.Buy
  • 2026-06-30Chardan CapitalBuy
  • 2026-06-17Leerink PartnersMarket Perform
  • 2026-05-13BernsteinMarket Perform

Competitors — APOC3

  • none identified

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.