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Annovis Bio Inc.distress 8/10 · high distress / dilution risk
$1.72-1%today-66% from 52w high
annovisbio.com7 employeesFounded 2008Malvern, PABiotechnology
Lead: Alzheimer's disease · est. market ~$8B (approx, global)
Revenue
pre-revenue
Liquidity
$14M
Runway
0.5 yrs
Shares 1y
+78%

Price & events

-44.0% over 6M
$1.59$2.32$3.06Jan 26Apr 26Jul 266.7Mdilution: 424B5 offering (2026-05-20)dilution: 424B5 offering (2026-05-19)dilution: 424B5 offering (2026-04-09)financing: 8-K material_agreement (2026-05-20)financing: 8-K material_agreement (2026-04-10)rating: Roth Capital: Buy (2026-07-08)rating: Canaccord Genuity: Buy (2026-04-14)
CatalystRating changeDilutionFinancingdashed = today
-1.4%
1D
-1.4%
1W
-1.4%
1M
-5.2%
3M
-43.0%
6M
-35.5%
1Y
-83.9%
2Y
-98.6%
5Y
-79.0%
All

Overview

Market Cap
$59.42M
Volume
29.50K
52 Week Range
$1.59 – $5.10
Total Shares
34.65M
Float Shares
30.67M
Short %
12.55%
% Held by Insiders
8.26%
% Held by Institutions
16.70%
RVOL
0.03x
Beta
1.19

Pipeline stages · 1 programs

buntanetap/posiphen
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2027-12

Pipeline · 2 trials · 2 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2027-12
Estimated 50%
readout ~2028-02-14
Phase 3buntanetap/posiphenEarly Alzheimers Diseaseactive not recruiting
2029-09
Estimated 50%
readout ~2029-11-15
Phase 2/3buntanetap/posiphenParkinson's Disease (PD), Deep Brain Stimulationrecruiting

Catalyst news & presentations · 4

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 34,646,868 · 5 offerings/1y · 0 PIPEs
  • 2026-05-208-Kmaterial_agreement
  • 2026-05-20424B5offering
  • 2026-05-19424B5offering
  • 2026-04-108-Kmaterial_agreement
  • 2026-04-09424B5offering
  • 2025-10-288-Kmaterial_agreement
  • 2025-10-28424B5offering
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

strong buy · target $11 (+541% upside) · 3 analysts
  • 2026-07-08Roth CapitalBuy
  • 2026-04-14Canaccord GenuityBuy
  • 2025-09-30Canaccord GenuityBuy
  • 2025-09-03HC Wainwright & Co.Buy
  • 2025-06-09HC Wainwright & Co.Buy
  • 2025-05-15Canaccord GenuityBuy

Competitors — Alzheimer's disease

  • GSKGSK plc$217.0B · D1
  • BMYBRISTOL MYERS SQUIBB CO$124.5B · D0
  • AXSMAxsome Therapeutics, Inc.$12.3B · D0
  • ACADACADIA PHARMACEUTICALS INC$4.2B · D0
  • DNLIDenali Therapeutics Inc.$3.6B · D2
  • NAMSNewAmsterdam Pharma Co N.V.$3.6B · D0
  • MPLTMapLight Therapeutics, Inc.$1.5B · D2
  • NMRANeumora Therapeutics, Inc.$281M · D5
  • PMNProMIS Neurosciences Inc.$125M · D5
  • INMBInmune Bio, Inc.$47M · D5

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.