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ANRO

Alto Neurosciencedistress 3/10 · well-funded / low risk
$26.71-2%today-5% from 52w high
altoneuroscience.com68 employeesFounded 2019Mountain View, CABiotechnology
Psychiatry / CNS 3
Lead: Major Depressive Disorder · est. market ~$16B (approx, global)
Revenue
pre-revenue
Liquidity
$264M
Runway
4.2 yrs
Shares 1y
+30%

Price & events

+55.5% over 6M
$14.11$21.09$28.07Jan 26Apr 26Jul 264.4Mdilution: 424B5 offering (2026-07-14)dilution: EFFECT shelf_effective (2026-04-20)dilution: S-3 shelf_registration (2026-04-10)financing: 8-K material_agreement (2026-07-14)financing: 8-K private_placement (2026-03-16)catalyst: PHASE2 ALTO-300 (2026-06-30) — click to opencatalyst: PHASE2 ALTO-207 (2026-06-30) — click to opencatalyst: PHASE2 ALTO-101 (2026-04-01) — click to opencatalyst: PHASE2 ALTO-101 (2026-02-01) — click to openrating: Baird: Outperform (2026-05-18)rating: Wedbush: Neutral (2026-05-14)rating: HC Wainwright & Co.: Buy (2026-05-11)rating: HC Wainwright& Co.: Buy (2026-05-11)rating: Chardan Capital: Buy (2026-04-22)rating: HC Wainwright & Co.: Buy (2026-04-02)rating: Jones Trading: Buy (2026-04-02)rating: Baird: Outperform (2026-04-02)
CatalystRating changeDilutionFinancingdashed = today
-1.9%
1D
-2.3%
1W
+9.3%
1M
+3.9%
3M
+60.8%
6M
+770.0%
1Y
+76.7%
2Y
5Y
+29.0%
All

Overview

Market Cap
$937.36M
Enterprise Value
$687.48M
Volume
10.46K
52 Week Range
$2.57 – $28.07
Total Shares
35.09M
Float Shares
22.76M
Short %
8.21%
% Held by Insiders
4.11%
% Held by Institutions
74.13%
RVOL
0.02x
Beta
1.07

Pipeline stages · 1 programs

ALTO-207
Preclin
Ph1
Ph2
Ph3
Filed
PDUFA
Approved
next 2026-08

Pipeline · 5 trials · 3 upcoming

ReadoutPhaseDrugIndicationEnrollStatus
2026-08
Estimated 50%
readout ~2026-09-15
Phase 2ALTO-100Bipolar Disorder I or II With a Major Depressive Episode200recruiting
2026-12
Estimated 50%
readout ~2027-01-15
Phase 2ALTO-300Major Depressive Disorderrecruiting
2027-11
Estimated 50%
readout ~2027-12-16
Phase 2ALTO-207Treatment-resistant Depression (TRD)recruiting
2026-02
Phase 2ALTO-101Schizophrenia, Cognitive Impairment82recruiting
2025-04-14
Phase 2ALTO-203 25 μg, ALTO-203 75 μgMajor Depressive Disorder, Anhedonia69completed

Catalyst news & presentations · 6

Approved drugs (0)

  • none — clinical-stage

Capital structure — dilution & financing

Shares out: 35,093,940 · 1 offerings/1y · 2 PIPEs
  • 2026-07-148-Kmaterial_agreement
  • 2026-07-14424B5offering
  • 2026-04-20EFFECTshelf_effective
  • 2026-04-10S-3shelf_registration
  • 2026-03-168-Kprivate_placement
  • 2025-12-10EFFECTshelf_effective
  • 2025-11-28S-3shelf_registration
🔒 Positioning — Pro
Short interest / days-to-cover, insider buys & sells.
Upgrade to Pro
🔒 Top holders — Pro
Institutional ownership + quarter-over-quarter accumulation/trimming.
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Wall St ratings

strong buy · target $35 (+32% upside) · 11 analysts
  • 2026-05-18BairdOutperform
  • 2026-05-14WedbushNeutral
  • 2026-05-11HC Wainwright & Co.Buy
  • 2026-05-11HC Wainwright& Co.Buy
  • 2026-04-22Chardan CapitalBuy
  • 2026-04-02HC Wainwright & Co.Buy

Competitors — Major Depressive Disorder

  • NBIXNEUROCRINE BIOSCIENCES INC$17.2B · D0
  • AXSMAxsome Therapeutics, Inc.$12.3B · D0
  • XENEXenon Pharmaceuticals Inc.$6.3B · D3
  • DFTXDefinium Therapeutics, Inc.$4.7B · D3
  • SUPNSUPERNUS PHARMACEUTICALS, INC.$2.7B · D0
  • BHVNBiohaven Ltd.$2.2B · D6
  • SPTXSeaport Therapeutics, Inc.$1.2B · D1
  • NMRANeumora Therapeutics, Inc.$281M · D5
  • HELPCYBIN INC.$175M · D5
  • TNXPTonix Pharmaceuticals Holding Corp.$170M · D7

Not financial advice. Data: ClinicalTrials.gov, SEC EDGAR, FINRA, Nasdaq, Yahoo.